Dall'11 aprile 2003 sono stati pubblicati 6910 articoli

AGGIORNAMENTO SCIENTIFICO PERMANENTE IN MEDICINA VETERINARIA

  Note tecniche

Questo archivio bibliografico contiene tutti i lavori scientifici pubblicati dal 1987 dalle riviste edite da SCIVAC prima e da EV srl poi, e lavori reperiti nella letteratura internazionale a partire dal 2001 in avanti. Per tutti i lavori è disponibile l'abstract, mentre per quelli italiani è disponibile anche il PDF originale (dal 1995).
La parola digitata nel campo [parola chiave] viene cercata in
[autori]
[titolo]
[abstract]
[parole chiavi]
Agendo sugli altri operatori (data, specie animale, rivista) si può rendere la ricerca più rapida e mirata.

  Riviste Italiane Indicizzate

Cinologia
Collana di Radiologia Clinica Ippologia
Large Animals Review
Medicina Felina
Notiziario Farmaceutico
Professione Veterinaria
Quaderni di Dermatologia
SISCA Observer
Veterinaria.


Totale Riviste pubblicate : 4784. Questa pagina mostra gli ultimi lavori inseriti.

Mercoledì, 29 Luglio 2020

M.I. Malik et al

Vota questo articolo
(0 Voti)

Genomics of subacute ruminal acidosis

  • Riferimento: Large Animal Review 2020; 26: 93-98
  • Abstract: The present review will present the most recent development in sub-acute ruminal acidosis (SARA) regarding high concentrate diet and its interaction on gene expression. The SARA is a common disorder in high producing ruminants. In addition SARA is a big challenge for ruminant nutritionists, therefore, the subject has been extensively studied in recent decades. In current decade nutrigenomic has been used to understand the cellular response influenced by high concentrate diet in ruminants. For sustainability of higher growth and production, animals are forced to feed on high concentrate and low fiber in diet. High concentrate diet leads to accumulation of higher concentration of VFA consequently ruminal pH decreases. Depression in pH for longer duration impairs ruminal epithelium tight junctions and hyperkeratosis. SARA is characterized by fewer tight junctions between cells, thinner cell layers, and an increased sloughing of the stratum corneum leading to a weakened permeability barrier. Ruminal epithelium serves as barrier for microbes, damages to ruminal epithelium leads to translocation of lipopolysaccharides (LPS) from compromised ruminal epithelium to blood circulation and different organs of the body. The LPS induce immunogenic response in ruminal papillae, epithelium, liver, and other organs. LPS induce a cascade mechanism of gene expression by binding with Tolllike receptor 4 (TLR4) a receptor for LPS, binding of LPS with TLR4 activate nuclear factor kappa B (NF-κB) consequently genes for interleukin 6 (IL), IL-8, tumor necrosis factor (TNF)-α and many more genes were up regulated or down regulated in rumen epithelium and other organs. In conclusion feeding high concentrate diets to ruminants’ triggered local and systemic inflammation response at molecular level. By exploring the mechanism of SARA and its effects on gene up regulation or down regulation can be a value able tools for understanding the SARA and its adverse effects on animal health and production performance.
  • Specie: animali da reddito
  • Anno: 2020
  • Rivista: Large Animals Review
Letto 6 volte Ultima modifica il Mercoledì, 29 Luglio 2020

SCIVAC Rimini Web

eveditoria Editoria Scientifica

Questo sito web utilizza cookie propri e di terze parti. Se chiudi il banner ne accetti l'utilizzo.